- Insulin Pump Therapy
- Patient Selection
- Initiating Pump Therapy
- Pump Settings
- Professional Reports
Intensive Insulin Therapy Helps Maximize
Glycemic Management in Type 1 Diabetes1
ADA recommendations for patients with type 1 diabetes include1*:
Use of multiple daily injections (MDI) or continuous subcutaneous insulin infusion (CSII) therapy, also known as insulin pump therapy
In a multinational study involving 11 treatment centers (N=229), CSII treatment resulted in2:
- Lower A1C
- Lower mean blood glucose level
- Marked reduction in the frequency of both mild and severe hypoglycemic events
- Higher overall score on the diabetes quality of life questionnaire
- Improvement in pump users' perception of mental health using the SF-12® Health Survey
*Matching of mealtime insulin and use of insulin analogs
Insulin Pumps Can Provide Robust Glycemic Control
There are 3 ways Medtronic insulin pumps help patients achieve robust glycemic control
Bayer CONTOUR® NEXT LINK Meter*
Delivery of insulin in 2 ways— basal insulin and bolus insulin
Bolus Wizard® calculator
*Bayer, the Bayer Cross and CONTOUR are registered trademarks of Bayer.
Insulin Pumps Use Rapid-Acting Insulin
Small doses of rapid-acting insulin, given evenly over each hour,
help keep the pharmacodynamics consistent
- The goal of basal insulin is to keep glucose concentrations stable in fasting states (during sleep and between meals) throughout the day
- In a clinical study,4 plasma glucose was maintained at target levels for:
- 11 hours using intermediate-acting insulin
- 15 hours using long-acting insulin
- 24 hours using insulin pump therapy with rapid-acting insulin
*N=20 patients with T1DM. Data are mean ± SE.
Adapted from Lepore M. et al. Diabetes. 2000;49: 2142-2128.
A Healthy Pancreas Produces Basal and Bolus Insulin*
Insulin pumps deliver insulin in a similar way - small amounts of rapid-acting insulin evenly over each hour throughout the day - larger amounts for food and to correct high blood glucose
Bolus Wizard® Helps Determine the Right Bolus Insulin Dose
The Bolus Wizard calculates each bolus dose for the patient using their current BG, carbohydrate intake and individualized pump settings (see more info below)5
Medtronic pumps include the Bolus Wizard feature, which:
- Automatically calculates the bolus insulin amount needed for each meal and the amount needed to correct high glucose levels
- Tracks the amount of active insulin the patient still has left from previous boluses, and subtracts it from a correction bolus before it suggests the amount of insulin the patient should take
Glucose Levels in a 41-Year-Old Male With Type 1 Diabetes*
Which of these charts shows the patient's glucose levels when the Bolus Wizard® was turned on?
Apart from the Bolus Wizard, all other pump settings were the same for both sets of blood glucose readings.
*Actual patient case. Scott Lee, MD. Loma Linda University Medical Center. Personal communication, 2009.
Results may vary from patient to patient and depend on the settings of the Bolus Wizard. Appropriate settings need to be determined.